Ibuprofen 400mg is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. Indications: Ibuprofen is effective in managing mild to moderate pain such as headaches, muscle aches, dental pain, back pain, menstrual cramps, and joint pain. It is also used to reduce fever and alleviate discomfort from common colds or flu. Additionally, it helps in conditions like arthritis, bursitis, and tendinitis. Off-Label Uses: Management of patent ductus arteriosus in premature infants Prevention of high-altitude headache Treatment of migraine headaches Pregnancy Safety: Ibuprofen is classified as Pregnancy Category D during the third trimester due to the risk of premature closure of the ductus arteriosus in the fetus and potential complications during labour. It should be avoided in the last trimester unless absolutely necessary and prescribed by a healthcare professional. Use during the first and second trimesters should be under medical supervision. Always consult a doctor before using Ibuprofen during pregnancy. Dosage and How to Take It: Adults and Children over 12 years: The usual recommended dose is 400mg every 4 to 6 hours as needed. Maximum Dose: Do not exceed 1200mg in a 24-hour period unless directed by a doctor. Administration Guidelines: Take Ibuprofen with food or a glass of milk to minimise stomach irritation. Swallow the tablet whole with water; do not crush or chew unless specified. Ensure adequate hydration while using this medication. If a dose is missed, take it as soon as remembered unless it’s near the time for the next dose. Do not double the dose. Important Precautions: Do not use if you have a history of allergic reactions to NSAIDs. Consult your doctor if you have conditions such as heart disease, high blood pressure, liver or kidney disease, or gastrointestinal issues. Avoid alcohol consumption while taking Ibuprofen to reduce the risk of stomach bleeding.